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Metagenomic resistome profiling tool trends

Citation adoption for curated metagenomic resistome profiling tools, counted weekly from OpenAlex.

DeepARG
most-cited · 932 citations
6
tools tracked
1
selected group
20152025
citation years
View
Y axis
01101002016201720182019202020212022202320242025citing-paper year · annual citations · log y-axisDeepARG · 189 citations in 2025 · peak 189/yr in 2025 · 932 lifetimeARGs-OAP · 135 citations in 2025 · peak 135/yr in 2025 · 709 lifetimeShortBRED · 32 citations in 2025 · peak 49/yr in 2021 · 366 lifetimePathoFact · 39 citations in 2025 · peak 45/yr in 2024 · 197 lifetimeAMR++ · 82 citations in 2025 · peak 82/yr in 2025 · 196 lifetimefARGene · 22 citations in 2025 · peak 23/yr in 2022 · 140 lifetimeDeepARGARGs-OAPAMR++PathoFactShortBREDfARGene
Hover a line, or focus a legend item, to see exact citation values. Click legend items to hide or show tools.
DeepARG
60
AMR++
53
ARGs-OAP
46
fARGene
36
ShortBRED
31
PathoFact
0
AMR++
active · this month
DeepARG
active · 2 mo ago
PathoFact
active · 4 mo ago
ShortBRED
active · 1.4 yr ago
fARGene
stale · 3.6 yr ago
ARGs-OAP
stale · 5.4 yr ago

Software health, not citations: GitHub/GitLab stars and last-commit date for each tool’s canonical source repo, as a point-in-time snapshot (2026-06-30). Bars in the last-commit chart show how recently each repo was touched — active, stale, archived or gone. Star bars are tinted to match each tool’s citation line above.

Use cumulative view for long-run adoption and annual view for citation momentum; log scale makes smaller tools readable without changing the counts. Counts are annual OpenAlex cited-by tallies and reflect all uses of each paper, not only use inside the selected workflow; broad tools can therefore look larger than workflow-specific methods. The still-filling current year (2026) is omitted from the lines.

10301003001.0K3.0K013612183672120169updated within 18 moARGs-OAP · amr-metagenomic · 135 citations in 2025fARGene · amr-metagenomic · 22 citations in 2025DeepARG · amr-metagenomic · 189 citations in 2025 · actively maintainedShortBRED · amr-metagenomic · 32 citations in 2025 · actively maintainedAMR++ · amr-metagenomic · 82 citations in 2025 · actively maintainedPathoFact · amr-metagenomic · 39 citations in 2025 · actively maintainedmonths since last update (√ scale) · 2025 citations (log scale)maintainedother

Each dot is one of 6 curated tools with a datable code repository (0 web-only / SourceForge tools without a public commit date aren't shown). Higher means more cited in 2025, the latest complete year (log scale); further left means more recently updated (square-root scale). Filled dots are actively maintained — a commit within the last 18 months. The upper-left gathers the field's well-kept, widely-used staples: fastp, SAMtools, DADA2, SPAdes, Prokka, DIAMOND and more, updated regularly and cited thousands of times a year. Maintenance and citations are only loosely linked (Spearman ρ ≈ −0.46): a citation counts every paper that mentions a method, so a quieter commit history does not mean a tool is unused or unmaintained — many stable, widely-relied-on tools rarely need new commits, and development sometimes moves to mirrors this snapshot can't see. Source: OpenAlex citation graph + GitHub/GitLab activity, as of 2026-06-25.

ShortBRED
’16–’19
DeepARG
’20–’25

The leading metagenomic resistome profiling tool is recomputed for each complete calendar year by cumulative citations — a 2-way hand-off across 10 years.

Cohort6 curated metagenomic resistome profiling tools
MetricCitations to each tool’s canonical method paper, counted by the citing paper’s publication year
MeasurementAnnual cited-by counts from OpenAlex (cites: grouped by year when available; counts_by_year fallback when the grouped endpoint is budget-limited)
Update cadenceWeekly automated re-count · latest snapshot 2026-06-25
Scope caveatCitation totals span every field that cites the paper, not only use inside the selected workflow — read them as overall reach
Recent-year caveatThe current year (2026) is still accruing citations, so it is dropped from the trend lines
Methodscripts/check-tool-trends.mjs
ToolGroupLifetime citationsPeak yearSourceStarsLast commitStatus
DeepARGMetagenomic resistome profiling9322025 (189/yr)GitHub602 mo agoactive
ARGs-OAPMetagenomic resistome profiling7092025 (135/yr)GitHub465.4 yr agostale
ShortBREDMetagenomic resistome profiling3662021 (49/yr)GitHub311.4 yr agoactive
PathoFactMetagenomic resistome profiling1972024 (45/yr)GitLab04 mo agoactive
AMR++Metagenomic resistome profiling1962025 (82/yr)GitHub53this monthactive
fARGeneMetagenomic resistome profiling1402022 (23/yr)GitHub363.6 yr agostale

A curated cohort of metagenomic resistome profiling tools, each tracked by the full citation history of its method paper — re-counted weekly straight from the OpenAlex citation graph. Only the published method papers and their public citation counts are used. · show all tool groups · back to all research data

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